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Hyoscine (Buscopan)Classification: Antispasmodic

Action: Inhibits acetylcholine at receptor sites in autonomic nervous system, which controls secretions, free acids to stomach; blocks central muscarinic receptors, which decreases involuntary movements.

Indication: Acute GI, biliary and genitourinary spasm, include biliary and renal colic, dysmenorrhea. Parenterally also as an aid in diagnostic and therapeutic procedures, e.g. gastroduodenal endoscopy, radiology.

Adverse Reactions: Xerostomia, tachycardia, urinary retention. When administered IV, visual accomodation disturbances, dizziness, agranulocytosis, pancytopenia and bronchospasm.

Nursing Considerations


  • Assess for eye pain; discontinue use
  • Monitor intake and output ratio; retention commonly causes decreased urinary output
  • Assess for parkinsonism, extra pyramidal symptoms
  • Assess for urinary hesitancy, retention, palpate bladder if retention occurs
  • Assess for constipation
  • Assess for tolerance over long term therapy
  • Assess mental status

Nursing Diagnoses

  • Fluid volume, deficit
  • Knowledge, deficit


  • SC/IM/IV route
    • Administer parenteral dose with sterile water; give slowly
    • Administer 3-4x/day
  • IV route
    • Give by direct IV after diluting with sterile water; give slowly


  • Tell patient to avoid hazardous activities requiring alertness; dizziness may occur
  • Inform patient that the drug passes into the breast milk and decrease milk flow; avoid drug or discontinue nursing until you finish medicine
  • Advise patient to avoid use of alcohol or other CNS depressants while taking medication
  • Explain that rinsing mouth, good oral hygiene, and sugarless gum or candy will help to counteract mouth dryness


  • Decreased secretions
  • Absence of motion sickness