Action: Inhibits acetylcholine at receptor sites in autonomic nervous system, which controls secretions, free acids to stomach; blocks central muscarinic receptors, which decreases involuntary movements.
Indication: Acute GI, biliary and genitourinary spasm, include biliary and renal colic, dysmenorrhea. Parenterally also as an aid in diagnostic and therapeutic procedures, e.g. gastroduodenal endoscopy, radiology.
Adverse Reactions: Xerostomia, tachycardia, urinary retention. When administered IV, visual accomodation disturbances, dizziness, agranulocytosis, pancytopenia and bronchospasm.
- Assess for eye pain; discontinue use
- Monitor intake and output ratio; retention commonly causes decreased urinary output
- Assess for parkinsonism, extra pyramidal symptoms
- Assess for urinary hesitancy, retention, palpate bladder if retention occurs
- Assess for constipation
- Assess for tolerance over long term therapy
- Assess mental status
- Fluid volume, deficit
- Knowledge, deficit
- SC/IM/IV route
- Administer parenteral dose with sterile water; give slowly
- Administer 3-4x/day
- IV route
- Give by direct IV after diluting with sterile water; give slowly
- Tell patient to avoid hazardous activities requiring alertness; dizziness may occur
- Inform patient that the drug passes into the breast milk and decrease milk flow; avoid drug or discontinue nursing until you finish medicine
- Advise patient to avoid use of alcohol or other CNS depressants while taking medication
- Explain that rinsing mouth, good oral hygiene, and sugarless gum or candy will help to counteract mouth dryness
- Decreased secretions
- Absence of motion sickness